A study of scalp melanoma — the largest conducted to date — has revealed the importance of scalp melanoma in the poor prognosis of head and neck melanoma. Results of the study, conducted by researchers at the John Wayne Cancer Institute in Santa Monica, California, were presented by Junko Ozao-Choy, MD, here at the Society of Surgical Oncology 65th Annual Cancer Symposium. “Scalp melanomas have a distinct presentation, compared with melanomas that occur on other body sites, and produce worse disease-free and overall survival than melanomas of the face and neck, trunk, and extremities,” Dr. Ozao-Choy told Medscape Medical News. This study established that head and neck melanomas are worse in terms of disease-free survival and overall survival than nonhead and neck melanomas. “We hypothesized that the scalp is associated with an outcome that is distinct from any other anatomic sites and that is responsible for the generally poor prognosis of head and neck melanoma,” Dr. Ozao-Choy told Medscape Medical News.